منابع مشابه
Golgi inheritance
Our view of what happens to the Golgi and ER during mitosis in mammalian cells has been shaken once more. Rather than the Golgi contents being recycled through, or mixed with the ER, two recent studies taking complementary approaches, find that the contents of these organelles remain separate throughout mitosis.
متن کاملGolgi architecture and inheritance.
Golgi inheritance proceeds via sequential biogenesis and partitioning phases. Although little is known about Golgi growth and replication (biogenesis), ultrastructural and fluorescence analyses have provided a detailed, though still controversial, perspective of Golgi partitioning during mitosis in mammalian cells. Partitioning requires the fragmentation of the juxtanuclear ribbon of interconne...
متن کاملGolgi Inheritance: Rab Rides the Coat-Tails
A recent study describes a role for a Rab GTPase previously implicated in endoplasmic reticulum and mitochondrial inheritance and for a COPI coatomer subunit in the targeting of a type V myosin to the late Golgi in yeast.
متن کاملGolgi inheritance: shaken but not stirred
What is the fate of the mammalian Golgi apparatus during mitosis? This seemingly simple question has become part of the wider debate concerning the nature of the Golgi apparatus and the mechanism of secretory protein transport. At the heart of this debate is the question of whether the Golgi is an organelle with its own separate identity, or a complex transport intermediate containing secretory...
متن کاملThe mitotic spindle mediates inheritance of the Golgi ribbon structure
The mammalian Golgi ribbon disassembles during mitosis and reforms in both daughter cells after division. Mitotic Golgi membranes concentrate around the spindle poles, suggesting that the spindle may control Golgi partitioning. To test this, cells were induced to divide asymmetrically with the entire spindle segregated into only one daughter cell. A ribbon reforms in the nucleated karyoplasts, ...
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ژورنال
عنوان ژورنال: Traffic
سال: 2001
ISSN: 1398-9219
DOI: 10.1034/j.1600-0854.2001.20901.x